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Nature Technology feature

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Nature Technology feature

What Are Nature Technology Features?

Nature Technology Features are editorially independent sections, spotlighting scientists and the technologies they choose. Each feature provides essential insights that can be readily implemented in laboratories around the world, making it the perfect platform for your brand to shine.

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2026 Nature Technology features calendar:

View the topics in more detail.

Publication date in 2026Nature Technology topicBooking deadline for branded content (Print and Online)Booking deadline for branded content (online only)Booking deadline for advertiser-supplied branded contentBooking deadline for display ad (submission of PDF)
22 January
Technologies to Watch
ONLINE ONLY24 October 2025N/A
19 March
PhD survey/AIONLINE ONLY18 December 2025
N/A
2 AprilSelf-driving labsONLINE ONLY16 January 2026N/A
7 MayMPRAsONLINE ONLY16 February 2026N/A
21 MayAntibiotic discovery/AIONLINE ONLY27 February 2026N/A
4 JuneVirtual cells/systems biology/PhysiCell (Fertig)ONLINE ONLY13 March 2026N/A
16 July

Epigenome editing (ie, CRISPR and variants)ONLINE ONLY27 April 2026N/A
30 July

What can’t we do with genome editors?ONLINE ONLY15 May 2026N/A
8 October Cell-free protein expressionONLINE ONLY29 July 2026N/A
  • PhD survey/AI (19 March)

    This article is an AI-focused follow-up to the PhD survey Careers features, about how PhD students are and are not using AI and their preferred tools. Basically, everyone is using AI, but nobody trusts it.

     

  • Self-driving labs (2 April)

    ’Self-driving labs’ are autonomous labs in which a combination of artificial intelligence and automation drive research forward without human intervention. The author will be visiting one such lab in Sweden to report on what these labs look like, how they work, what they can and cannot do, and how researchers can work with them.

     

  • MPRAs (7 May)

    MPRAs, or ‘massively parallel reporter assays’, are used to measure the gene-regulatory activity of a vast number of DNA sequences at once. Among other things, MPRAs provide the data to inform ‘genome AI’ systems that can ‘dream up’ new sequences with a desired activity (for instance, new regulatory DNAs that function in a particular cell type for gene therapy applications. see https://www.nature.com/articles/d41586-025-02621-8). They have other applications too, and our author will be focusing on those as well.

     

  • Antibiotic discovery/AI (21 May)

    How artificial intelligence is being used to for antibiotic discovery. There are basically two ways to do this: 1) using AI to infer from genome sequences what metabolites an organism might be capable of synthesizing, then creating and testing those; or 2) using AI to imagine entirely new molecules.

     

  • Virtual cells / systems biology / PhysiCell (Fertig) (4 June)

    Virtual cells, ie detailed computer/AI simulations of how cells work. Basically, a series of mathematical models that in total describe some or all of a particular biochemical process. This article will focus on what these are, how they work, what people might do with them, and their status. (The Chan-Zuckerberg Initiative is pouring money into this at the moment.) Among other things, this relates to tools for collecting cellular ‘perturbation’ data, such as “Perturb-seq” —  if you want to know how a system works, you have to systematically break it in different ways and see how the system reacts.

     

  • Epigenome editing (16 July)

    We all know about genome editing systems like CRISPR/Cas. Epigenome editing uses variants of these systems not to change DNA sequence but rather how they are chemically modified in the cell. These modifications (such as methylation or acetylation) change how the DNA is read in the cell — that is, they can influence whether a gene is expressed or not, regardless of its sequence.

     

  • What can’t we do with genome editors? (30 July)

    Genome editing tools such as Prime editing and base editors are based on the popular CRISPR-Cas9 gene-editing system. But Cas9 creates double-stranded breaks in DNA that complicate the editing process — sometimes those breaks are corrected using a mechanism that can introduce mutations instead of the desired change. In contrast, prime editing and base editing tools alter the sequence of DNA without these damaging breaks. They look especially promising for human gene therapy and related applications, where precise genome modifications are required. But for all their nimbleness, these editors (and other editing approaches) still cannot do everything. In this feature, we look at the different approaches and consider what they can and cannot do, and what technological gaps researchers still hope to close.

     

  • Cell-free protein expression (8 October)

    Cell-free protein expression’ refers to systems that allow researchers to express a given protein using either crude cellular extracts or by mixing purified proteins. This has applications for biomanufacturing, because it allows researchers to control the environment in which, say, biopharmaceuticals are synthesized. (As opposed to, say, producing them inside cells, from which the desired material must them be purified.)

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