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gorkem8d/README.md

Hi, I'm Görkem 👋

Computational biologist building reproducible pipelines for genomics and transcriptomics analysis. I combine wet-lab expertise with software engineering to solve problems in disease genomics and single-cell biology.

🔬 About Me

  • 🎓 Dual MSc in Molecular & Cellular Biology (LMU Munich) and Computer Engineering (Boğaziçi University)
  • 🧬 Focused on variant analysis, single-cell RNA-seq, and pipeline automation
  • 📊 Published researcher in computational biology and synthetic biology
  • 💻 Building scalable bioinformatics tools for translational research

🛠️ Technical Stack

Programming & Tools:
Python • R • Snakemake • SLURM • Git • Linux/Unix

Bioinformatics:
GATK • 10x Genomics Chromium • Scanpy • CellTypist • scRNA-seq analysis • Variant calling pipelines

Computational:
High-performance computing (HPC) • Workflow automation • Machine learning for biological data

📚 Selected Publications

View all publications →

🔭 Current Work

Working on computational pipelines for evolutionary genomics and transcriptomics-based variant discovery in complex diseases. Interested in single-cell technologies, spatial omics, and AI applications in biology.

📫 Connect With Me


Open to bioinformatics software engineering and computational biology opportunities

Pinned Loading

  1. Variant-discovery-using-transcriptomics-data Variant-discovery-using-transcriptomics-data Public

    A study to identify novel genetic variants that might contribute to complex disease pathogenesis by leveraging cost-effective and publicly available RNA-seq data that captures variants in actively …

    Jupyter Notebook 1

  2. Custom_protein_domain_identification Custom_protein_domain_identification Public

    Computational pipeline for systematic protein domain identification using anchor-based coordinate normalization. Combines de novo motif discovery (MEME) with genome-wide scanning (FIMO) to map cons…

    Jupyter Notebook

  3. neuroepigenetics-data-science/TF_cobinding_multiome_chrombpnet neuroepigenetics-data-science/TF_cobinding_multiome_chrombpnet Public

    Regulatory genomics pipeline for discovering co-binding transcription factors in cell-type-specific enhancers, built on ChromBPNet + TF-MoDISco.

    R

  4. neuroepigenetics-data-science/TF_cobinding_multiome_tobias neuroepigenetics-data-science/TF_cobinding_multiome_tobias Public

    implementing TOBIAS to discover footprints

    Python